Fotbolldirekt Syn Act Pharma initierar RESOVIR Vetenskapligt och

Nordic Life Science - issue 4 2020 - E-magin - Tulo

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SynAct Pharma expects to soon receive approval to initiate a Phase II clinical trial in Covid-19 patients with the drug candidate AP1189. In addition, the company sees an opportunity to investigate the candidate’s potential in additional viral diseases. A common denominator in all indications is the great potential to counteract the often fatal hyperinflammation that […] SynAct Pharma AB today announced the initiation of a Phase II clinical study to evaluate the safety and efficacy of the company's lead candidate drug AP1189 in adults diagnosed with COVID-19 and with AP1189 –a melanocortin receptor agonist to reduce inflammation and “boost” healing First indication: activeinflammatory joint diseases (rheumatoid and psoriatic arthritis) Opportunity: additional indications based on Mode of Action (ACTH-like properties) 2020-06-30 · AP1189 Study. The Phase II study for AP1189 will be double-blind, multi-center, and placebo-controlled. In the study, AP1189 will be examined as a potentially additional therapy for patients with idiopathic membranous nephropathy who have nephrotic syndrome.

Klinisk prövning på Reumatoid artrit: 50 mg AP1189, AP1189

In vivo, oral AP1189 elicited anti-inflammatory actions in peritonitis and, upon administration at the peak of inflammation, accelerated the resolution phase by ∼3-fold. An exploratory, randomized, double-blind, multicenter, placebo-controlled study to assess the safety, tolerability, pharmacokinetics, and efficacy of AP1189 daily doses versus placebo administered for 4 weeks as an add-on to patients, in ACE inhibitor or angiotensin II receptor blocker treatment, with idiopathic membranous nephropathy - SynAct Nordic Life Science News. Nordic Life Science 1 CLINICAL TRIALS PH A SE I I The company has start ed a Phase II clinical study to evaluate the safety and efficacy of the company’s lead candidate drug AP1189 in adults diagnosed with COVID-19 and with early signs of Acute Respiratory Distress Syndrome (ARDS).

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More. Fotbolldirekt Syn Act Pharma initierar RESOVIR Vetenskapligt och kliniskt samarbete för att utforska AP1189 i virala infektioner o wtnoitavlasmodgnik Sweden The latest Tweets from Bjänn (@Bjaentrading).

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Norra Skåne Syn Act slutför del 1 av klinisk fas II studie med AP1189

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Mauro Teixeira at Universidade Federal de Minas, Belo Horizonte, Brazil. The trial design, which has been approved by the authorities in Brazil, is based upon strong scientific evidence supporting the role of AP1189 in modulating inflammatory responses.